Ọnọdụ akpụkpọ ahụ, ịdị arọ ahụ, ịrụ ọrụ usoro obi na usoro ndị ọzọ na-edozi ahụ na-achịkwa site na homonụ. A na-emepụta ha site na glands ndị pụrụ iche - gland na aditeal gland. Ọ bụrụ na arụ ọrụ nke akụkụ ahụ na-emebi, njedebe endocrine apụtaghị.
Nsogbu Isenko-Cushing - gini ka ọ bụ?
Ọnọdụ a kọwara (hypercorticosis) bụ otu ụdị ọrịa nke cortex adrenal na-emepụta ọtụtụ cortisol ma ọ bụ hormonon adrenocorticotropic. Ọ dị mkpa ịmata ọdịiche dị n'etiti nsogbu a na-atụle na ọrịa Cushing. Ọ bụ ọnụọgụ nke abụọ nke usoro endocrine, na-emepe megide ọrịa nke hypothalamus na ụbụrụ pituitary.
Ọrịa Cushing - Ihe kpatara
E nwere ọtụtụ ihe nwere ike ịkpasu ihe a aka. A na - emepụta ihe niile na - akpata hypercorticism na ụdị atọ:
- ọhụụ;
- njedebe;
- arụ ọrụ.
Nnukwu hypercorticosis
Ọrịa a nke Itenko-Cushing na-amalite n'okpuru nduzi nke ihe ndị ọzọ. Isi ihe kpatara ya bụ ịnọgide na-eji glucocorticosteroid hormones. Ụdị ọrịa a sitere na ọgwụgwọ, ya mere a na-akpọkwa ya hypercorticism. A na-ahụkarị ya mgbe a sụgharịrị - a na-etinye ọgwụ mgbochi ọgwụ iji gbochie nsogbu ma gbochie ịjụ akụkụ ahụ transplanted. Ọrịa ịgwọ ọrịa ọgwụ na-amalitekwa site n'ịgwọ ọrịa ọkụ na-adịghị ala ala:
- ọrịa ogbu na nkwonkwo;
- ụkwara ume ọkụ;
- systemic lupus erythematosus.
Mmechi hypercorticosis
Nke a dị iche iche nke ọrịa ahụ na-eme n'ihi nsogbu ndị dị n'ime ahụ. Isi ihe kpatara mmepe bụ ọnọdụ na-eduga nkwụsị nke adteal cortex:
- hyperplasia ;
- cancer;
- benign neoplasm;
- dystrophy.
Iji kpalite mmụba nke etuto ahụ nwere ike ịbụ ịkwa iko, ya mere, otu n'ime ihe kpatara mmetọ hypercorticism bụ ọdịdị mkpụrụ ndụ. Ọ bụ neoplasms kpatara ọrịa Itenko-Cushing, ma n'akụkụ ndị ọzọ:
- pituitary gland;
- ovaries;
- ọkụ;
- thymus;
- nyocha;
- pancreas ma ọ bụ thyroid gland;
- bronchi.
Ọrịa na-akpata ọrịa Cushing
E nwere ọnọdụ nke mmepụta cortisol na-emepụta, ma ọ dịghị ọgwụ mgbochi-na-ezobe ahụ n'ahụ. Nke a bụ ọrịa ọrịa nke ọrịa hypercorticism, ọ na-esonyere ọrịa nyocha na nke uche. Maka mmebi iwu nke a na-ahụ anya nke ọma, dị ka ezigbo ọrịa ahụ. Mgbe ụfọdụ, ọrịa Pseudo-syndrome Itenko-Cushing kpaliri:
- ibu;
- ime ime;
- aṅụrụma (ịṅụbiga mmanya ókè);
- ọbara mgbali ;
- mmebi nke carbohydrate metabolism.
Ọrịa Itenko-Ịgba ume - mgbaàmà
Akụkụ bụ isi nke hypercorticism bụ nchịkọta abụba n'ọtụtụ ebe:
- n'olu;
- isi;
- afọ;
- obi.
N'ihi oke ibu, ọ dịdị mfe ile anya na ọrịa Itenko-Cushing, ihe mgbaàmà ya bụ:
- gburugburu ihu;
- akụkụ ụkwụ na-ekwesịghị ekwesị ma ọ bụrụ na e jiri ya tụnyere ahụ;
- acha odo odo-acha anụnụ anụnụ na-agbapụta n'elu akpa, hips, afo, ubu;
- ịda mbà n'obi na ụbụrụ na-adabere na ibu arọ na ọdịdị na-adịghị mma.
N'adịghị ọgwụgwọ, mgbatị hormonal na-esiwanye njọ. Ịzụlite ọrịa Cushing na-aga n'ihu, ihe mgbaàmà nke bụ:
- oke ntutu isi na nwanyi (hirsutism na nwoke);
- ọbara mgbali elu;
- nsogbu ndị na-eme ka ọ ghara ịdị na-aga;
- adịghị ike;
- myopathy;
- osteoporosis ma jikọta ya na mgbe ọkpụkpụ ọkpụkpụ;
- isi ọwụwa;
- ehighi ura;
- nsogbu uche;
- adịghị ike;
- akwara atrophy;
- abaminal hernia;
- ọsụsọ;
- ihe otutu ;
- hyperpigmentation nke ụfọdụ akpụkpọ anụ;
- nkwụsị nke ọkpụkpụ azụ;
- akwara afọ abdominal;
- arụ ọrụ nke usoro nchịkwa ahụ;
- enwu gbaa.
Isenko-Cushing syndrome - nyocha
Isi ihe na-enye ohere iji chee na hypercorticism bụ ihe mgbaàmà nke ọrịa. Mgbe ha na-achikota emenesis na nyocha nke oma, onye nlekota onu ogugu na-enye usoro omumu iji mata ihe kpatara nsogbu ndi ozo, ihe di iche iche nke oria a mara na nsogbu ndi ozo. Nsogbu Cushing - nchọpụta:
- nyocha nke mmamịrị na ọbara na ọdịnaya nke hormones corticosteroid;
- redio nke ógbè Turkish na akwa okpokoro;
- kọmputa ma ọ bụ ihe ndọtị na-ahụ maka magnetik nke pituitary na grenic adrenal;
- ihe nlele dexamethasone;
- ọgwụ biochemistry nke ọbara;
- X-ray nke azụ na azụ;
- scintigraphị nke adrenal glands.
Isenko-Cushing syndrome - ọgwụgwọ
Usoro ọgwụgwọ na-adabere na ihe kpatara ịkpata ọbara ọbara. Na ihe ndị dị egwu, mmefusị nwayọọ nwayọọ, iwepụta ọgwụ nke glucocorticoids ma ọ bụ ndị na-agbanye ha site na ọgwụ ndị ọzọ na-egbochi ọrịa. N'ikwekọ, a na-eme ọgwụgwọ nke ọrịa Itenko-Cushing, nke e ji mee ihe iji weghachite usoro nke metabolic na normalizing arọ ahụ.
N'ihe banyere nsogbu nke cortisol mepụtara, a ghaghị iwepụ ya. Nanị nhọrọ dị irè na ọnụnọ ụbụrụ nke na-akpalite ọrịa Cushing na-emeso ya. E wepụrụ Neoplasm, sụgharịa redio na usoro ọgwụgwọ ogologo oge. Họrọ ndị na-ahụ maka ọgwụ na-eme ka ndị mmadụ ghara ịmịkọrọ ọbara ọbara ma gbochie mmepụta ha:
- Ọka;
- Aminoglutethimide;
- Mammoth na ndị ọzọ.
Na mgbakwunye, ọ dị mkpa ịkwụsị mgbaàmà nke ọrịa. Iji mee nke a, jiri (na nhọrọ nke endocrinologist):
- nkwadebe nke potassium;
- ọgwụ antihypertensive;
- nri;
- vitamin na mineral;
- ọgwụ hypoglycemic;
- nghazi;
- bisphosphonates;
- ụbụrụ anabolic;
- ndị na-eme nri;
- antidepressants.
Nutrition maka hypercortisy
Nri adịghị enyere aka belata mmepụta nke cortisol, mana ga-eme ka normalization nke usoro metabolic na ahụ. Ọ dị mkpa iji gbochie hypercorticism - ọgwụgwọ gụnyere mmezi nke nri na njigide ma ọ bụ wepụ ngwaahịa ndị na-esonụ:
- margarine;
- anụ anụmanụ;
- Mayonezi;
- bọta;
- ihe na-ese anwụrụ;
- nnu;
- anụ mara abụba na azụ;
- nri;
- ụgbọ mmiri;
- ntụtụ;
- ike tii na kọfị;
- mmanya;
- sweets.
Iji dozie ọrịa Itzenko-Cushing ọ dị mkpa iji:
- àkwá;
- mmiri ara ehi mmiri ara ehi;
- chiiz siri ike;
- obere abụba ma ọ bụ nri anụ anaghị eri anụ;
- uzo;
- esi nri;
- mkpụrụ osisi na akwụkwọ nri;
- elu;
- ọgwụ herbal;
- enweghi acid achikota na ihe ọṅụṅụ ihe ọṅụṅụ.
Nsogbu nke ọrịa Itenko-Cushing
Ihe a na-atụle na ọ dị mfe ịga n'ihu, na enweghi ọgwụgwọ zuru oke ọ pụrụ iduga nnukwu nsogbu. Ọrịa ahụ na ọrịa Itenko-Cushing na-ejikọta nsogbu dị otú ahụ:
- ọrịa strok;
- mgbapụta nke ọrụ obi;
- sepsis;
- chronic renal failure;
- nnukwu pyelonephritis;
- ǹyọkọ;
- otutu akpụkpụ ọkpụkpụ;
- ihe na-enweghị ike imebi ihe ọkpụkpụ azụ;
- nnyeòhèrè
- ịkpụ nkume akụrụ;
- Fungal na ọnya akpụkpọ anụ na mbido;
- ime ọpụpụ;
- nnyefe mgbagwoju anya.
Mgbe ụfọdụ ọrịa ma ọ bụ ọrịa nke Itenko-Cushing na-akpata ọnọdụ dị oke egwu nke nwere ike ịkwụsị nsogbu na - egbu egbu (adrenal). Ihe ịrịba ama ya:
- hypoglycemia;
- nnukwu mgbu n'ime afọ;
- mmeri na-enweghị obi ụtọ;
- hyperkalemia;
- ọnwụ nke nsụhọ;
- a na-egbusi ike na mgbali ọbara;
- hyponatremia;
- metabolic acidosis.