Ọrịa Antiphospholipid na afọ ime

Ọrịa Antiphospholipid (APS) bụ otu nsogbu ọrịa autoimmune nke e ji mara ọtụtụ ọgwụ nje na phospholipids dị na plasma ọbara (antiphospholipid antibodies). N'etiti ụmụ nwanyị na-ata ahụhụ site na ọpụpụ na-emekarị , nsogbu nke ọrịa antiphospholipid dị elu, ọ dịkwa 28-43%. Isi ihe mgbagwoju anya a bu thrombosis.

Kedu ihe bụ isi kpatara ọganihu nke APS?

Ihe kpatara nsogbu nke ọrịa antiphospholipid bụ ole na ole. Ụdị ọrịa a nwere ike ịmalite n'ọnọdụ ndị a:

1. Mgbe nwanyị na-arịa ọrịa na systemic lupus erythematosus .
2. Ịga n'ihu na emenesis nke thrombosis. Mgbe arịa ụbụrụ nke na-enye ọbara na eriri afọ, ihe a na-akpọ "abadinal toad" na-amalite, nke a na-ahụ nke ọdịdị nke ịpị ịchịcha, nke na-enwe nrụgide na abdominal ozugbo ozugbo ingestion.
3. Mbelata nke platelets n'ime ọbara, nke na-esonyere site na ihe omimi phenomena.
4. Ọnụnọ nke akụkọ ihe mere eme nke infarction myocardial na ọrịa ndị ọzọ metụtara ọrịa ọbara obi.

Kedu ka ọrịa antiphospholipid si gosipụta?

Mgbaàmà nke ọrịa antiphospholipid, na-adabere na ọtụtụ ihe. Ihe dị mkpa dị ezigbo mkpa:

• okpuru na ebe nke arịa ndị metụtara ọrịa ahụ;
• usoro nke ichikota lumen n'ime ha.

Ya mere, na ikpe mgbe enwere mkpọchi nke obere ụgbọ mmiri, a na-ahụ obere mmebi nke ọrụ nke akụkụ ahụ na-eri na ha. Dịka ọmụmaatụ, ọ bụrụ na enwere ọgba aghara nke obere vascular reticulums, enwere ihe na-emebi ọgbụgba nke akụkụ ọ bụla nke myocardium, ma ọ bụrụ na a na-emechi lumen nke akwara coronary, a ga-eme ka ịmịnye ọkpụkpụ myocardial.

Ọtụtụ mgbe ọrịa ọrịa antiphospholipid na ụmụ nwanyị dị ime nwere ike imetụta ụdị ọrịa ndị ọzọ, nke a na-eji otu mgbaàmà ahụ. Ya mere, ihe ịrịba ama nke ọrịa antiphospholipid nwere ike igosi ya n'ihu ọnụ lyvedo (lacy, mgbatị nke mmiri na akpụkpọ anụ). Ọzọkwa, ọrịa ọnya na-adịghị ala ala, bụ nke siri ike ịgwọ, na ọbụna gangrene ime ụlọ, nwere ike igosi ọnụnọ nke ọrịa a na ahụ.

Kedu ka e si eme ọgwụgwọ?

A na-agwọ ọrịa ọrịa antiphospholipid na ime ime n'okpuru nchịkwa nke ndị dọkịta abụọ: ọkachamara n'ọrịa na ọkà mmụta sayensị. Usoro ọgwụgwọ nke usoro a bụ iji glucocorticoids na cytostatics. N'ịdị elu nke ọgwụ nje na ọbara, naanị ihe ngwọta bụ ime ihe plasmapheresis (ịsacha ọbara).