Nwa gị malitere ịrịa ọrịa, dọkịta ahụ na-enyekwa ya nyocha ọbara. Dị ka ihe si na ya pụta, ọ pụtara na ọbara nwatakịrị amụbawo ogo nke phosphatase alkaline. Ndị nne na nna, n'ezie, jụọ onwe ha ozugbo ihe phosphatase dị na ya bụ maka ọrụ na ihe bụ ihe ngosi.
Kedu ihe alkaline phosphatase na-egosi?
Alkaline phosphatase bụ otu nke enzymes dị n'ime ihe fọrọ nke nta ka ọ bụrụ akụkụ nile nke ahụ mmadụ. Otutu phosphatase alkaline di n'onu ogugu, osteoblast, dule ducts. A na-agụnye ụda olu nke eriri afọ. A na-emepụta phosphatase alkaline site na akwa oyi akwa nke mucosa intestinal, mana ọ na-ekere òkè na nchịkọta mgbaze maka oge nke abụọ. Isi ọrụ nke alkaline phosphatase bụ cleavage nke phosphoric acid, nke dị mkpa maka ahụ, site na ihe dị iche iche ogige organic. Nke a na enzyme na-enyekwa aka na njem nke site n'ime ahụ.
A na-ewere ọdịnaya nke alkaline phosphatase n'ime ụmụaka dị ka ihe nkịtị:
- mgbe a mụrụ -
- n'ụbọchị nke ise mgbe a mụsịrị nwa -
- site na ụbọchị 6 ruo ọnwa 6 -
- site na ọnwa isii rue afọ 1 -
- site na otu afọ ruo afọ atọ -
- site na 4 ruo afọ 6 -
- site na afọ asaa ruo afọ 12 -
- site na afọ 13 rue afọ 17 (ụmụ nwoke) -
- site na afọ 13 rue afọ 17 (ụmụ agbọghọ) -
Ọnụego nke enzyme a na ọbara ọbara nwere ike ịdị iche iche dabere na ụzọ nke nnyocha na ndị reagents ji.
N'ihe gbasara ịrịa ụmụaka, ihe nrịba nke alkaline phosphatase na-arụ ọrụ dị mkpa n'ime nyocha ọrịa nke ọrịa imeju, tinyere ọnụ na bilele na-eruba na duodenum. N'okwu a, alkaline phosphatase n'ime ọbara nwatakịrị na-arịwanye elu. Ọdịdị kasị elu nke phosphatase na-eme mgbe enwere mmebi nke bile n'ihi na nkume na bile duct ma ọ bụ na etuto nke bile ducts. Tụkwasị na nke ahụ, na-ebu ọkwa phosphatase dị elu n'ime nwatakịrị, dọkịta ahụ nwekwara ike itinye ndị nyocha dị otú a:
- ọrịa ọkpụkpụ, gụnyere etuto ahụ, sarcome, metastases na-egbu egbu na ọkpụkpụ;
- hyperparathyroidism;
- mmeri nke ọkpụkpụ na lymphogranulomatosis;
- rickets;
- Ọrịa Paget (ọrịa skeletal);
- nje mononucleosis;
- myeloma;
- cytomegaly ụmụaka;
- ọrịa nje.
Nke dị oke mkpa bụ ihe ngosipụta nke alkaline phosphatase n'ime ụmụ maka nyocha nke mmalite nke rickets. N'okwu a, ọrụ mmezigharị na-ebili ogologo oge tupu ọrịa ahụ pụta ìhè.
Mgbe ụfọdụ, e nwere usoro mmụta ahụike, nke bụ, eke, na-arịwanye elu na ọkwa alkaline phosphatase na ọbara ọbara: na ụmụ ọhụrụ ma ọ bụ na-eto eto n'oge ha na-eto eto ma na-eto eto nke ọkpụkpụ anụ.
Mgbe ị na-aṅụ ọgwụ ọjọọ nke nwere mmetụta ọkpụkpụ hepatotoxic, enwere ike ibuli elu nke enzyme alkaline phosphatase n'ime nwatakịrị. Ndị ọgwụ ndị a gụnyere paracetamol, penicillins, sulfonamides, erythromycin na ọtụtụ ndị ọzọ. Site na mmụba metabolism na ọkpụkpụ ọkpụkpụ n'oge a na-agbaji ọkpụkpụ ọkpụkpụ, a na-ebuli elu nke enzyme a.
Lowering the level of the enzyme alkaline phosphatase abụghị nke ịrịba Clinical mkpa. Mbelata na ọkwa nke enzyme nwere ike imebi mmebi nke ọkpụkpụ, enweghị nri na zinc, magnesium, vitamin C na B12, na anaemia na hypothyroidism, na
Kedu ka esi belata phosphatase alkaline?
Iji gosi na ọkwa nke alkaline phosphatase na nwa ahụ ga-alaghachi na nkịtị, ọ dị mkpa iji agwọ ọrịa ahụ, ọ bụghị naanị iji dozie ọkwa a na iwu.
Na ụmụaka, ọrụ nke phosphatase alkaline na-adịkarị elu karịa ndị okenye. N'ọnọdụ ụfọdụ, ụba ọrụ nke phosphatase bụ nanị ihe ịrịba ama nke ọrịa ọrịa imeju. Ya mere, ọ dị ezigbo mkpa ime nchọpụta ọmụmụ niile dị mkpa ma malite ịgwọ nwa gị na oge, nke ga-eme ka ọ gbakee ngwa ngwa.